11月 4, 2018

英国论文:阿霉素纳米颗粒

英国论文:阿霉素纳米颗粒

阿霉素被发现是从蒽环霉素中提取的,蒽环霉素是细胞毒性的,是从白衣原体培养物中分离得到的。发现这些化合物基于平面抗花青素核的特定嵌入以及DNA的双螺旋结构与核酸结合。 它被发现阻碍体内癌细胞的生长。 阿霉素阻断酶拓扑异构酶的功能。 这是癌细胞增殖所必需的。 在这种情况下考虑的一些因素是基于组织暴露的药物功效。

英国论文:阿霉素纳米颗粒

商业和毒性是考虑的其他一些因素。人们对临床癌症及其生物学因素的异质性有了更好的理解。在配方驱动的研究中已经观察到一种转变,即疾病驱动的发展。纳米医学需要开发,潜力需要得到充分利用。

英国论文:阿霉素纳米颗粒

Doxorubicin is found to be extracted from the anthracycline antibiotic that is cytotoxic and isolated from the Streptomyces peucetius cultures. These compounds are found to bind to the nucleic acid based on the specific intercalation of the planar antracyanine nucleus along with the double helical structure of the DNA. It is found to impede the growth of the Cancer cells in the body. The doxorubicin blocks the function of the enzyme topo isomerase 2. This is needed by the cancer cells to proliferate. Some of the factors that are considered in this situation are the efficacy of the drug based on the exposure of the tissue.

英国论文:阿霉素纳米颗粒

The commerce and the toxicity are some of the other factors that are considered. There has been an improved comprehension of the heterogeneity of clinical cancers and its biological factors. There is a transition that has been observed in the case of formulation-driven research to it being disease driven development. The nanomedicine needs to be developed and the potential needs to be fully harnessed.

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