Tissue Engineering can be defined as the method used to improve or replace the function of biological tissues. Regenerative medicine in the current times has grown owing to the development of tissue engineering technology. They primarily use the progenitor cells to produce tissues . Scaffolds are generated owing to this technology.
However, in spite of the potential of these tissues engineering, they have not been fully utilized. There is the issue of developing innovative methods for the functional use of the scaffolds. Currently, the costs involved in production is said to be very high and they impede the development of this technology. One of the main limitations of this issue is the costs involved in the production. The costs are high for the tissue engineering because there are direct costs involved in the production and other indirect costs that differ based on the subjective nature of the patients. Hence it becomes very difficult to determine the costs involved in the process.
Important milestones in the production and areas of limitation
3D printing is a new technology that is used for the development of tissue engineering scaffolds. This is a cost effective approach that is used for the development of scaffolds. 3D complexity is mimicking the multicellular interactions . They need to be factored in the development of scaffold. The greatest challenge is producing a multiple cell sources that are customized to the patient needs. Polymer hydrogels, composite and cell aggregates can be developed by using the 3D manufacturing processes.
These are found to be a viable alternative that is cheaper but there is more nuanced technology that should be developed to meet the precise needs. More accurate developments and heuristic process need to be considered. This has been the limitation of the current 3D models. This needs to be developed in the future research .
Another important promising delivery is the Nano fibrous materials and the use of Nano material for the development of the scaffold. The issue with the Nano Materials is that they are costly and also the cytotoxicity is higher. There is a need for more technology to reduce the toxicity impacts of the Nano materials. Precise and accurate development of the technology is possible using Nano materials but the real issue with the Nano materials is the innate costs involved and the toxicity factor that should be addressed.
Pluripotent stem cells are the conventional technology that is used for the development of scaffolds. These progenitor cells are found to be extremely useful in the areas of tissue engineering. This has been in practice for more than 20 years. But the costs involved in the process and the experimentation costs involved are very high. This has impeded the commercial production of the tissue engineering . There is a need to develop these stems cells using innovative newer technology
Purpose of the thesis is to improve the production of the regenerative product and to reduce costs in the production. These factors need to be developed in the current environment. This analysis will look into ways to optimize cost and increasing the production.