代谢工程在东方的形成中起着重要的作用。介绍了改进工业发酵工艺的工程方法。代谢工程这门学科是不断改进的，它比以前想象的要复杂得多。最初，有一个用于修改的工具的可用性的动态开发。评估和建模代谢通量越来越明显，增强细胞活动需要对整个细胞的整体认识，而不是遥远的代谢途径。目前，代谢工程被认为是一个包含多轮代谢通量的工程、评估、分析和建模的交互式程序(Curran et al.， 2013)。传统的代谢工程是理性加演绎的，可以说是理性和建设性的。目前，理性代谢工程包括酶工程、转运体、调控蛋白、途径信息等。
The metabolic engineering is important in the formation of the east. The engineering approaches to improve the industrial fermentation process. The discipline of the metabolic engineering is subject to constant improvement, and it is much more complicated than perceived before. Initially, there is the dynamic development of the availability of tools for modifying. Evaluating and modeling metabolic fluxes is increasingly obvious that enhancing the cellular actions require the holistic perceptions of the entire cell rather than remote metabolic pathways. Currently, the metabolic engineering is perceived as an interactive procedure inclusive of many rounds of the engineering, evaluation, analysis as well as modeling of the metabolic fluxes (Curran et al., 2013). The conventional metabolic engineering is rational plus deductive and it can be referred to as the rational and constructive. At present, the rational metabolic engineering includes the enzymes engineering, transporters, and regulatory protein, information of the pathways, etc.
The improvement of the Saccharomyces cerevisiae is falling into the second category for the equipping the yeast with the help of supplemental enzymes. The supplemental enzymes are consisting of the amylases, proteases, lipases and the hemicellulases. These enzymes are identified for providing the quality food production processes with also taking part in the quality drug production processes also. This includes the CO2 production and the dough fermentation. The maltose is consisting of the efficient fermentation of the dough sugars, and also the yeast cells are playing a crucial role in the process of the dough leavening. This limiting factor in the case of the fermentation is increasing the rate by showing the repression of the maltose-utilizing enzymes (Mosier and Ladisch, 2009). The inactivation of this enzyme becomes essential, and this is resulting in the lag phase maltose consumption. This can be easily avoided by depressing the utilization of the maltose enzymes and the replacement of the native parameters are seen this case.